CD4+ T Cell‐Released Extracellular Vesicles Potentiate the Efficacy of the HBsAg Vaccine by Enhancing B Cell Responses

CD4+ T Cell‐Released Extracellular Vesicles Potentiate the Efficacy of the HBsAg Vaccine by Enhancing B Cell Responses

Abstract T cells secrete bioactive extracellular vesicles (EVs), but the potential biological effects of CD4+ T cell EVs are not clear. The main purpose of this study is to investigate the effects of CD4+ T cell–derived EVs on B cell responses and examine their role in antigen‐mediated humoral immun...

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Bibliographic Details
Main Authors: Jian Lu, Jing Wu, Feiting Xie, Jie Tian, Xinyi Tang, Hongye Guo, Jie Ma, Ping Xu, Lingxiang Mao, Huaxi Xu, Shengjun Wang
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Advanced Science
Subjects:
B cells
CD4+ T cells
CD40L
extracellular vesicles
HBsAg vaccine
Online Access:https://doi.org/10.1002/advs.201802219

Internet

https://doi.org/10.1002/advs.201802219

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