K Index is a Reliable Marker of Intrathecal Synthesis, and an Alternative to IgG Index in Multiple Sclerosis Diagnostic Work-Up

K Index is a Reliable Marker of Intrathecal Synthesis, and an Alternative to IgG Index in Multiple Sclerosis Diagnostic Work-Up

The K free light chain (K) index has been suggested as a reliable marker of intrathecal synthesis, despite the 2017 McDonald criteria for multiple sclerosis (MS) suggesting to “interpret with caution positive immunoglobulin G (IgG) index when testing for oligoclonal bands (OB) is negative...

Full description

Bibliographic Details
Main Authors: Ilaria Crespi, Domizia Vecchio, Roberto Serino, Elena Saliva, Eleonora Virgilio, Maria Giovanna Sulas, Giorgio Bellomo, Umberto Dianzani, Roberto Cantello, Cristoforo Comi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Journal of Clinical Medicine
Subjects:
cerebrospinal fluid
diagnosis
immunoglobulins
Online Access:https://www.mdpi.com/2077-0383/8/4/446

Internet

https://www.mdpi.com/2077-0383/8/4/446

Similar Items