Neuroinflammation and the Kynurenine Pathway in CNS Disease: Molecular Mechanisms and Therapeutic Implications

Neuroinflammation and the Kynurenine Pathway in CNS Disease: Molecular Mechanisms and Therapeutic Implications

Diseases of the central nervous system (CNS) remain a significant health, social and economic problem around the globe. The development of therapeutic strategies for CNS conditions has suffered due to a poor understanding of the underlying pathologies that manifest them. Understanding common etiolog...

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Bibliographic Details
Main Authors: Mustafa N. Mithaiwala, Danielle Santana-Coelho, Grace A. Porter, Jason C. O’Connor
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
affective disorders
depression
kynurenine pathway
microglia
neuroinflammation
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/10/6/1548

Internet

https://www.mdpi.com/2073-4409/10/6/1548

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