Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial.

Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input. The aim of the present study is to evaluate the effect of pregabali...

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Bibliographic Details
Main Authors: Stefan A W Bouwense, Søren S Olesen, Asbjørn M Drewes, Jan-Werner Poley, Harry van Goor, Oliver H G Wilder-Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412837?pdf=render