MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular features.

To describe the frequency of MLH1 promoter methylation in colorectal cancer (CRC); to explore the associations between MLH1 promoter methylation and clinicopathological and molecular factors using a systematic review and meta-analysis.A literature search of the PubMed and Embase databases was conduc...

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Bibliographic Details
Main Authors: Xia Li, Xiaoping Yao, Yibaina Wang, Fulan Hu, Fan Wang, Liying Jiang, Yupeng Liu, Da Wang, Guizhi Sun, Yashuang Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612054?pdf=render