The Role of Canonical Transient Receptor Potential Channels in Seizure and Excitotoxicity

Canonical transient receptor potential (TRPC) channels are a family of polymodal cation channels with some degree of Ca2+ permeability. Although initially thought to be channels mediating store-operated Ca2+ influx, TRPC channels can be activated by stimulation of Gq-coupled G-protein coupled recept...

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Bibliographic Details
Main Authors: Fang Zheng, Kevin D. Phelan
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/3/2/288