Porous COS@SiO2 Nanocomposites Ameliorate Severe Acute Pancreatitis and Associated Lung Injury by Regulating the Nrf2 Signaling Pathway in Mice

Porous COS@SiO2 Nanocomposites Ameliorate Severe Acute Pancreatitis and Associated Lung Injury by Regulating the Nrf2 Signaling Pathway in Mice

Severe acute pancreatitis (SAP) is associated with high rates of mortality and morbidity. Chitosan oligosaccharides (COSs) are agents with antioxidant properties. We developed porous COS@SiO2 nanocomposites to study the protective effects and mechanisms of COS nanomedicine for the treatment of acute...

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Bibliographic Details
Main Authors: Qixiang Mei, Guoying Deng, Zehua Huang, Yue Yin, Chunlin Li, Junhui Hu, Yang Fu, Xingpeng Wang, Yue Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Chemistry
Subjects:
severe acute pancreatitis
lung injury
oxidative stress
porous COS@SiO2 nanocomposites
Nrf2 signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00720/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00720/full

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