Selective disruption of the cerebral neocortex in Alzheimer's disease.

Alzheimer's disease (AD) and its transitional state mild cognitive impairment (MCI) are characterized by amyloid plaque and tau neurofibrillary tangle (NFT) deposition within the cerebral neocortex and neuronal loss within the hippocampal formation. However, the precise relationship between pat...

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Bibliographic Details
Main Authors: Rahul S Desikan, Mert R Sabuncu, Nicholas J Schmansky, Martin Reuter, Howard J Cabral, Christopher P Hess, Michael W Weiner, Alessandro Biffi, Christopher D Anderson, Jonathan Rosand, David H Salat, Thomas L Kemper, Anders M Dale, Reisa A Sperling, Bruce Fischl, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2944799?pdf=render