Mycobacterial tlyA gene product is localized to cell-wall without signal sequence.

Mycobacterial tlyA gene product is localized to cell-wall without signal sequence.

The mycobacterial tlyA gene product, Rv1694 (MtbTlyA), has been annotated as 'hemolysin' which was re-annotated as 2'-O rRNA methyl transferase. In order to function as a hemolysin, it must reach extracellular milieu with the help of signal sequence(s) and/or transmembrane segment(s)....

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Bibliographic Details
Main Authors: Santosh eKumar, Ekansh eMittal, Sapna eDeore, Anil eKumar, Aejazur eRahman, Krishnasastry V Musti
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
outer membrane vesicles
signal sequences
Membrane fractions
protein secretion pathways
TlyA gene product
Cell-wall localization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00060/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00060/full

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