Patient-Derived Organoid Models of Human Neuroendocrine Carcinoma

Patient-Derived Organoid Models of Human Neuroendocrine Carcinoma

Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) is a poorly understood disease with limited treatment options. A better understanding of this disease would greatly benefit from the availability of representative preclinical models. Here, we present the potential of tumor organoids, three-d...

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Bibliographic Details
Main Authors: Krijn K. Dijkstra, José G. van den Berg, Fleur Weeber, Joris van de Haar, Arno Velds, Sovann Kaing, Dennis D. G. C. Peters, Ferry A. L. M. Eskens, Derk-Jan A. de Groot, Margot E. T. Tesselaar, Emile E. Voest
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
extrapulmonary neuroendocrine carcinoma
disease modeling
pre-clinical models
organoids
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.627819/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.627819/full

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