A Case Report of Germline Compound Heterozygous Mutations in the <i>BRCA1</i> Gene of an Ovarian and Breast Cancer Patient

A Case Report of Germline Compound Heterozygous Mutations in the <i>BRCA1</i> Gene of an Ovarian and Breast Cancer Patient

The germline carrier of the <i>BRCA1</i> pathogenic mutation has been well proven to confer an increased risk of breast and ovarian cancer. Despite <i>BRCA1</i> biallelic pathogenic mutations being extremely rare, they have been reported to be embryonically lethal or to cause...

Full description

Bibliographic Details
Main Authors: Ava Kwong, Cecilia Y. S. Ho, Vivian Y. Shin, Chun Hang Au, Tsun Leung Chan, Edmond S. K. Ma
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
hereditary breast cancer
<i>compound heterozygous mutations</i>
Chinese
Fanconi anemia
Online Access:https://www.mdpi.com/1422-0067/22/2/889

Internet

https://www.mdpi.com/1422-0067/22/2/889

Similar Items