Prdx1 Reduces Intracerebral Hemorrhage-Induced Brain Injury via Targeting Inflammation- and Apoptosis-Related mRNA Stability

Prdx1 Reduces Intracerebral Hemorrhage-Induced Brain Injury via Targeting Inflammation- and Apoptosis-Related mRNA Stability

RNA-binding proteins (RBPs) have been shown to be involved in posttranscriptional regulation, which plays an important role in the pathophysiology of intracerebral hemorrhage (ICH). Peroxiredoxin 1 (Prdx1), an RBP, plays an important role in regulating inflammation and apoptosis. On the basis that i...

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Bibliographic Details
Main Authors: Guo-Qiang Yang, Jia-Cheng Huang, Jun-Jie Yuan, Qin Zhang, Chang-Xiong Gong, Qiong Chen, Qi Xie, Le-Xing Xie, Ru Chen, Zhong-Ming Qiu, Kai Zhou, Rui Xu, Guo-Hui Jiang, Xiao-Yi Xiong, Qing-Wu Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroscience
Subjects:
RNA-binding protein
peroxiredoxin 1
intracerebral hemorrhage
inflammation
apoptosis
posttranscriptional regulation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00181/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00181/full

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