Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy

Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy

Chemokine-like factor (CKLF)-like MARVEL transmembrane domain containing 6 (CMTM6) modulates degradation of a number of proteins, including programmed death ligand-1 (PD-L1) by protecting it from ubiquitin-mediated degradation. In this role, it could modulate the effectiveness of immunotherapy. Here...

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Bibliographic Details
Main Authors: Sandra Martinez-Morilla, Jon Zugazagoitia, Pok Fai Wong, Harriet M. Kluger, David L. Rimm
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
cmtm6
pd-l1
melanoma
immune cells
quantitative immunofluorescence
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1864909

Internet

http://dx.doi.org/10.1080/2162402X.2020.1864909

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