Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

Immunotherapy has reshaped the field of cancer therapeutics but the population that benefits are small in many tumor types, warranting a companion diagnostic test. While immunohistochemistry (IHC) for programmed death-ligand 1 (PD-L1) or mismatch repair (MMR) and polymerase chain reaction (PCR) for...

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Bibliographic Details
Main Authors: Ioannis A. Vathiotis, Zhi Yang, Jason Reeves, Maria Toki, Thazin Nwe Aung, Pok Fai Wong, Harriet Kluger, Konstantinos N. Syrigos, Sarah Warren, David L. Rimm
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00184-1

Internet

https://doi.org/10.1038/s41698-021-00184-1

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