Intrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines
<p>Abstract</p> <p>Background</p> <p>One of the major reasons for poor prognosis of pancreatic cancer is its high resistance to currently available chemotherapeutic agents. In recent years, focal adhesion kinase (FAK), a central molecule in extracellular matrix (ECM)/in...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-12-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/8/1/125 |