Systems genetics of liver fibrosis: identification of fibrogenic and expression quantitative trait loci in the BXD murine reference population.

The progression of liver fibrosis in response to chronic injury varies considerably among individual patients. The underlying genetics is highly complex due to large numbers of potential genes, environmental factors and cell types involved. Here, we provide the first toxicogenomic analysis of liver...

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Bibliographic Details
Main Authors: Rabea A Hall, Roman Liebe, Katrin Hochrath, Andrey Kazakov, Rudi Alberts, Ulrich Laufs, Michael Böhm, Hans-Peter Fischer, Robert W Williams, Klaus Schughart, Susanne N Weber, Frank Lammert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938463?pdf=render