Structural insights into SETD3-mediated histidine methylation on β-actin

Structural insights into SETD3-mediated histidine methylation on β-actin

SETD3 is a member of the SET (Su(var)3–9, Enhancer of zeste, and Trithorax) domain protein superfamily and plays important roles in hypoxic pulmonary hypertension, muscle differentiation, and carcinogenesis. Previously, we identified SETD3 as the actin-specific methyltransferase that methylates the...

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Bibliographic Details
Main Authors: Qiong Guo, Shanhui Liao, Sebastian Kwiatkowski, Weronika Tomaka, Huijuan Yu, Gao Wu, Xiaoming Tu, Jinrong Min, Jakub Drozak, Chao Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
X-ray crystallography
post translational modifications
β-actin
SET domain
N3-methylhistidine
Online Access:https://elifesciences.org/articles/43676

Internet

https://elifesciences.org/articles/43676

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