Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line

Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line

Melanoma represents one of the most aggressive and drug resistant skin cancers with poor prognosis in its advanced stages. Despite the increasing number of targeted therapies, novel approaches are needed to counteract both therapeutic resistance and the side effects of classic therapy. Betulinic aci...

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Bibliographic Details
Main Authors: Dorina Coricovac, Cristina Adriana Dehelean, Iulia Pinzaru, Alexandra Mioc, Oana-Maria Aburel, Ioana Macasoi, George Andrei Draghici, Crina Petean, Codruta Soica, Madalina Boruga, Brigitha Vlaicu, Mirela Danina Muntean
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
betulinic acid
melanoma
mitochondria
OXPHOS
glycolysis
apoptotic markers
Online Access:https://www.mdpi.com/1422-0067/22/9/4870

Internet

https://www.mdpi.com/1422-0067/22/9/4870

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