TRPV1 translocated to astrocytic membrane to promote migration and inflammatory infiltration thus promotes epilepsy after hypoxic ischemia in immature brain

TRPV1 translocated to astrocytic membrane to promote migration and inflammatory infiltration thus promotes epilepsy after hypoxic ischemia in immature brain

Abstract Background Neonatal hypoxic-ischemic brain damage (HIBD), a leading cause of neonatal mortality, has intractable sequela such as epilepsy that seriously affected the life quality of HIBD survivors. We have previously shown that ion channel dysfunction in the central nervous system played an...

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Bibliographic Details
Main Authors: Xin Wang, Xing-Liang Yang, Wei-Lin Kong, Meng-Liu Zeng, Lin Shao, Guang-Tong Jiang, Jing-Jing Cheng, Shuo Kong, Xiao-Hua He, Wan-Hong Liu, Tao-Xiang Chen, Bi-Wen Peng
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
TRPV1
Inflammation
Astrocytes
HIBD
Epilepsy
Online Access:http://link.springer.com/article/10.1186/s12974-019-1618-x

Internet

http://link.springer.com/article/10.1186/s12974-019-1618-x

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