Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice [v1; ref status: indexed, http://f1000r.es/2wb]
The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have supported the involvement of dynein, the major motor for r...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2014-03-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | http://f1000research.com/articles/3-68/v1 |