Enhancement of the Acrolein-Induced Production of Reactive Oxygen Species and Lung Injury by GADD34

Chronic obstructive pulmonary disease (COPD) is characterized by lung destruction and inflammation. As a major compound of cigarette smoke, acrolein plays a critical role in the induction of respiratory diseases. GADD34 is known as a growth arrest and DNA damage-related gene, which can be overexpres...

Full description

Bibliographic Details
Main Authors: Yang Sun, Sachiko Ito, Naomi Nishio, Yuriko Tanaka, Nana Chen, Lintao Liu, Ken-ichi Isobe
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/170309