Zika Virus Requires the Expression of Claudin-7 for Optimal Replication in Human Endothelial Cells

Zika Virus Requires the Expression of Claudin-7 for Optimal Replication in Human Endothelial Cells

Zika virus (ZIKV) infection has been associated with a series of neurological pathologies. In patients with ZIKV-induced neurological disorders, the virus is detectable in the central nervous system. Thus, ZIKV is capable of neuroinvasion, presumably through infection of the endothelial cells that c...

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Bibliographic Details
Main Authors: Jim Zoladek, Vincent Legros, Patricia Jeannin, Maxime Chazal, Nathalie Pardigon, Pierre-Emmanuel Ceccaldi, Antoine Gessain, Nolwenn Jouvenet, Philippe V. Afonso
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Microbiology
Subjects:
flavivirus
Zika virus
claudin
endothelial cells
infection
blood-brain barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.746589/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.746589/full

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