Unraveling Heterogeneity of Tumor Cells and Microenvironment and Its Clinical Implications for Triple Negative Breast Cancer

Unraveling Heterogeneity of Tumor Cells and Microenvironment and Its Clinical Implications for Triple Negative Breast Cancer

Objective: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer, characterized by extensive intratumoral heterogeneity. We aimed to systematically characterize the tumor heterogeneity of TNBC.Methods: Single-cell RNA sequencing (scRNA-seq) of TNBC cells were obtained from t...

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Bibliographic Details
Main Authors: Ke Jiang, Mengting Dong, Chunyang Li, Jiayu Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
triple negative breast cancer
single-cell RNA-seq
immune cells
heterogeneity
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.557477/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.557477/full

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