Effects of Sorafenib and Arsenic Trioxide on U937 and KG-1 Cell Lines: Apoptosis or Autophagy?

Effects of Sorafenib and Arsenic Trioxide on U937 and KG-1 Cell Lines: Apoptosis or Autophagy?

Objective: Acute myeloid leukemia (AML) is a clonal disorder of hemopoietic progenitor cells. The Raf serine/threonine (Ser/Thr) protein kinase isoforms including B-Raf and RAF1, are the upstream in the MAPK cascade that play essential functions in regulating cellular proliferation and survival. A...

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Bibliographic Details
Main Authors: Atousa Haghi, Mahdieh Salami, Mahnaz Mohammadi Kian, Mohsen Nikbakht, Saeed Mohammadi, Bahram Chahardouli, Shaharbano Rostami, Kianoosh Malekzadeh
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-10-01
Series:Cell Journal
Subjects:
acute myeloid leukemia
apoptosis
arsenic trioxide
cell proliferation
sorafenib
Online Access:https://celljournal.org/journal/article/abstract/6728

Internet

https://celljournal.org/journal/article/abstract/6728

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