Effects of Sorafenib and Arsenic Trioxide on U937 and KG-1 Cell Lines: Apoptosis or Autophagy?
Objective: Acute myeloid leukemia (AML) is a clonal disorder of hemopoietic progenitor cells. The Raf serine/threonine (Ser/Thr) protein kinase isoforms including B-Raf and RAF1, are the upstream in the MAPK cascade that play essential functions in regulating cellular proliferation and survival. A...
Main Authors: | Atousa Haghi, Mahdieh Salami, Mahnaz Mohammadi Kian, Mohsen Nikbakht, Saeed Mohammadi, Bahram Chahardouli, Shaharbano Rostami, Kianoosh Malekzadeh |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2020-10-01
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Series: | Cell Journal |
Subjects: | |
Online Access: | https://celljournal.org/journal/article/abstract/6728 |
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