Critical steps to tumor metastasis: alterations of tumor microenvironment and extracellular matrix in the formation of pre-metastatic and metastatic niche

Critical steps to tumor metastasis: alterations of tumor microenvironment and extracellular matrix in the formation of pre-metastatic and metastatic niche

Abstract For decades, cancer metastasis has been a heated topic for its high mortality. Previous research has shown that pre-metastatic niche and metastatic niche are the 2 crucial steps in cancer metastasis, assisting cancerous cells’ infiltration, survival, and colonization at target sites. More r...

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Bibliographic Details
Main Authors: Jianan Zhuyan, Mingyu Chen, Tianhao Zhu, Xunxia Bao, Timing Zhen, Kaichen Xing, Qiubo Wang, Sibo Zhu
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cell & Bioscience
Subjects:
ECM components
Metastasis
Organ specificity
Mechanism
Systematic literature review
Online Access:http://link.springer.com/article/10.1186/s13578-020-00453-9

Internet

http://link.springer.com/article/10.1186/s13578-020-00453-9

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