Detection and Distinction of Mild Brain Injury Effects in a Ferret Model Using Diffusion Tensor MRI (DTI) and DTI-Driven Tensor-Based Morphometry (D-TBM)

Detection and Distinction of Mild Brain Injury Effects in a Ferret Model Using Diffusion Tensor MRI (DTI) and DTI-Driven Tensor-Based Morphometry (D-TBM)

Mild traumatic brain injury (mTBI) is highly prevalent but lacks both research tools with adequate sensitivity to detect cellular alterations that accompany mild injury and pre-clinical models that are able to robustly mimic hallmark features of human TBI. To address these related challenges, high-r...

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Bibliographic Details
Main Authors: Elizabeth B. Hutchinson, Susan C. Schwerin, Kryslaine L. Radomski, Neda Sadeghi, Michal E. Komlosh, M. O. Irfanoglu, Sharon L. Juliano, Carlo Pierpaoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neuroscience
Subjects:
diffusion tensor MRI
ferret
controlled cortical impact
mild traumatic brain injury
tensor-based morphometry
white matter
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00573/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00573/full

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