Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in Mice

Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in Mice

Genetic variants in the fat mass- and obesity-associated gene Fto are linked to the onset of obesity in humans. The causal role of the FTO protein in obesity is supported by evidence obtained from transgenic mice; however, the underlying molecular pathways pertaining to the role of FTO in obesity ha...

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Bibliographic Details
Main Authors: Justiina Ronkainen, Eleonora Mondini, Francesca Cinti, Saverio Cinti, Sylvain Sebért, Markku J. Savolainen, Tuire Salonurmi
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:International Journal of Molecular Sciences
Subjects:
FTO
brown adipose tissue (BAT)
white adipose tissue (WAT) browning
gene expression
microRNA expression
high-fat diet
Online Access:http://www.mdpi.com/1422-0067/17/11/1851

Internet

http://www.mdpi.com/1422-0067/17/11/1851

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