Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci.

Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci.

Genome-wide association studies of two main forms of inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), have identified 99 susceptibility loci, but these explain only 23% of the genetic risk. Part of the 'hidden heritability' could be in transmissible...

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Main Authors: Karin Fransen, Mitja Mitrovic, Cleo C van Diemen, B K Thelma, Ajit Sood, Andre Franke, Stefan Schreiber, Vandana Midha, Garima Juyal, Uros Potocnik, Jingyuan Fu, Ilja Nolte, Rinse K Weersma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3459955?pdf=render

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http://europepmc.org/articles/PMC3459955?pdf=render

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