Rational Design and Synthesis of New, High Efficiency, Multipotent Schiff Base-1,2,4-triazole Antioxidants Bearing Butylated Hydroxytoluene Moieties

Rational Design and Synthesis of New, High Efficiency, Multipotent Schiff Base-1,2,4-triazole Antioxidants Bearing Butylated Hydroxytoluene Moieties

A new series of multipotent antioxidants (MPAOs), namely Schiff base-1,2,4-triazoles attached to the oxygen-derived free radical scavenging moiety butylated hydroxytoluene (BHT) were designed and subsequently synthesized. The structure-activity relationship (SAR) of the designed antioxidants was est...

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Bibliographic Details
Main Authors: Wageeh A Yehye, Noorsaadah Abdul Rahman, Omar Saad, Azhar Ariffin, Sharifah Bee Abd Hamid, Abeer A. Alhadi, Farkaad A. Kadir, Marzieh Yaeghoobi, Abdulsalam A. Matlob
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
butylated hydroxytoluene
PASS
1,2,4-triazole
Schiff base
DPPH assay
Online Access:http://www.mdpi.com/1420-3049/21/7/847

Internet

http://www.mdpi.com/1420-3049/21/7/847

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