Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy

This review is focused on different subsets of T cells: CD4 and CD8, memory and effector functions, and their role in CAR-T therapy––a cellular adoptive immunotherapy with T cells expressing chimeric antigen receptor. The CAR-T cells recognize tumor antigens and induce cytotoxic activities against t...

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Bibliographic Details
Main Authors: Vita Golubovskaya, Lijun Wu
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/3/36