Amifostine Pretreatment Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Apoptosis and Oxidative Stress

The present study was aimed at investigating the effect of amifostine on myocardial ischemia/reperfusion (I/R) injury of mice and H9c2 cells cultured with TBHP (tert-butyl hydroperoxide). The results showed that pretreatment with amifostine significantly attenuated cell apoptosis and death, accompan...

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Bibliographic Details
Main Authors: Shao-ze Wu, Lu-yuan Tao, Jiao-ni Wang, Zhi-qiang Xu, Jie Wang, Yang-jing Xue, Kai-yu Huang, Jia-feng Lin, Lei Li, Kang-ting Ji
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/4130824