Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9Research in the context

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9Research in the context

Background: Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenesis, the mechanism underlying this relationship rema...

Full description

Bibliographic Details
Main Authors: Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305449

Internet

http://www.sciencedirect.com/science/article/pii/S2352396418305449

Similar Items