Isocratic high-performance liquid chromatography (HPLC) for simultaneous quantification of curcumin and piperine in a microparticle formulation containing Curcuma longa and Piper nigrum

Poor bioavailability has been reported as a major challenge in the development of curcumin as a pharmaceutical agent. However, co-administration of curcumin with piperine has been shown to improve curcumin bioavailability. Therefore, to assure product control quality, an analytical method needs to b...

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Bibliographic Details
Main Authors: Dewi Setyaningsih, Yosua Agung Santoso, Yustina Sri Hartini, Yosi Bayu Murti, Wouter L.J. Hinrichs, Christine Patramurti
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021006447