Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells.

Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells.

Ophiobolin A, a fungal toxin from Bipolaris species known to affect different cellular processes in plants, has recently been shown to have anti-cancer activity in mammalian cells. In the present study, we investigated the anti-proliferative effect of Ophiobolin A on human melanoma A375 and CHL-1 ce...

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Bibliographic Details
Main Authors: Carlo Rodolfo, Mariapina Rocco, Lucia Cattaneo, Maria Tartaglia, Mauro Sassi, Patrizia Aducci, Andrea Scaloni, Lorenzo Camoni, Mauro Marra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5147944?pdf=render

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http://europepmc.org/articles/PMC5147944?pdf=render

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