Downregulation of lncRNA-11496 in the Brain Contributes to Microglia Apoptosis via Regulation of Mef2c in Chronic T. gondii Infection Mice

Downregulation of lncRNA-11496 in the Brain Contributes to Microglia Apoptosis via Regulation of Mef2c in Chronic T. gondii Infection Mice

Though it is well known that chronic infections of Toxoplasma gondii (T. gondii) can induce mental and behavioral disorders in the host, little is known about the role of long non-coding RNAs (lncRNAs) in this pathological process. In this study, we employed an advanced lncRNAs and mRNAs integration...

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Bibliographic Details
Main Authors: Xiahui Sun, Ting Wang, Yongliang Wang, Kang Ai, Ge Pan, Yan Li, Chunxue Zhou, Shenyi He, Hua Cong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
HDAC2
long non-coding RNA
Mef2c
microglia
Toxoplasma gondii
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00077/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00077/full

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