Scopoletin and umbelliferone from Cortex Mori as protective agents in high glucose-induced mesangial cell as in vitro model of diabetic glomerulosclerosis

Scopoletin and umbelliferone from Cortex Mori as protective agents in high glucose-induced mesangial cell as in vitro model of diabetic glomerulosclerosis

Two known coumarins, scopoletin (SP) and umbelliferone (UB), were isolated from Cortex Mori (CM). Their structures were elucidated by various spectroscopic analyses. Then, their effects on rat glomerular mesangial cells (RGMCs, HBZY-1) proliferation, hypertrophy, extracellular matrix (ECM) prolifera...

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Bibliographic Details
Main Authors: Yijun Liang, Xuxin Zeng, Jialiang Guo, Hui Liu, Bao He, Renyu Lai, Quan Zhu, Zhaoguang Zheng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Chinese Journal of Physiology
Subjects:
cortex mori
diabetic kidney disease
glomerulosclerosis
proliferation
rat glomerular mesangial cells
scopoletin
umbelliferone
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=3;spage=150;epage=158;aulast=Liang

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http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=3;spage=150;epage=158;aulast=Liang

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