NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages.

NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages.

Blood monocytes are recruited to injured tissue sites and differentiate into macrophages, which protect against pathogens and repair damaged tissues. Reactive oxygen species (ROS) are known to be an important contributor to monocytes' differentiation and macrophages' function. NF-E2-relate...

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Bibliographic Details
Main Authors: Min-Gu Song, In-Geun Ryoo, Hye-Young Choi, Bo-Hyun Choi, Sang-Tae Kim, Tae-Hwe Heo, Joo Young Lee, Pil-Hoon Park, Mi-Kyoung Kwak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519053?pdf=render

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http://europepmc.org/articles/PMC4519053?pdf=render

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