Combination of Solvent Displacement and Wet Ball Milling Techniques for Size Reduction of Celecoxib

Background: The objective of the present study was to investigate the combinative effect of ball milling and solvent displacement method on size reduction of Celecoxib particles. Celecoxib is a poorly water soluble cyclooxygenase 2 inhibitor which has a wide range of therapeutic applicability. Metho...

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Bibliographic Details
Main Author: Shadi Yaqoubi, Mohammad Barzegar Jalali, Khosro Adibkia, Hamed Hamishehkar
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-03-01
Series:Pharmaceutical Sciences
Online Access:http://journals.tbzmed.ac.ir/PHARM/Abstract/PHARM_827_20150912180525