Paracrine effects of bone marrow soup restore organ function, regeneration, and repair in salivary glands damaged by irradiation.

Paracrine effects of bone marrow soup restore organ function, regeneration, and repair in salivary glands damaged by irradiation.

BACKGROUND: There are reports that bone marrow cell (BM) transplants repaired irradiated salivary glands (SGs) and re-established saliva secretion. However, the mechanisms of action behind these reports have not been elucidated. METHODS: To test if a paracrine mechanism was the main effect behind th...

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Bibliographic Details
Main Authors: Simon D Tran, Younan Liu, Dengsheng Xia, Ola M Maria, Saeed Khalili, Renee Wan-Jou Wang, Vu-Hung Quan, Shen Hu, Jan Seuntjens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634855?pdf=render

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http://europepmc.org/articles/PMC3634855?pdf=render

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