Meningococcal factor H binding proteins in epidemic strains from Africa: implications for vaccine development.

Factor H binding protein (fHbp) is an important antigen for vaccines against meningococcal serogroup B disease. The protein binds human factor H (fH), which enables the bacteria to resist serum bactericidal activity. Little is known about the vaccine-potential of fHbp for control of meningococcal ep...

Full description

Bibliographic Details
Main Authors: Rolando Pajon, Andrew M Fergus, Oliver Koeberling, Dominique A Caugant, Dan M Granoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3167780?pdf=render