Proximity of Substantia Nigra Microstimulation to Putative GABAergic Neurons Predicts Modulation of Human Reinforcement Learning

Proximity of Substantia Nigra Microstimulation to Putative GABAergic Neurons Predicts Modulation of Human Reinforcement Learning

Neuronal firing in the substantia nigra (SN) immediately following reward is thought to play a crucial role in human reinforcement learning. As in Ramayya et al. (2014a) we applied microstimulation in the SN of patients undergoing deep brain stimulation (DBS) for the treatment of Parkinson's di...

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Bibliographic Details
Main Authors: Ashwin G. Ramayya, Isaac Pedisich, Deborah Levy, Anastasia Lyalenko, Paul Wanda, Daniel Rizzuto, Gordon H. Baltuch, Michael J. Kahana
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Human Neuroscience
Subjects:
substantia nigra
human
dopamine
GABA
neuron
reinforcement learning
Online Access:http://journal.frontiersin.org/article/10.3389/fnhum.2017.00200/full

Internet

http://journal.frontiersin.org/article/10.3389/fnhum.2017.00200/full

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