Restoration of high-sensitivity and adapting vision with a cone opsin

Activating the spared neurons downstream of rods and cones is a potential therapeutic approach for retinal degeneration, but has been limited by the characteristics of the opsins available. Here, the authors use medium wavelength cone opsin which has faster kinetics than others and show that it reso...

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Bibliographic Details
Main Authors: Michael H. Berry, Amy Holt, Autoosa Salari, Julia Veit, Meike Visel, Joshua Levitz, Krisha Aghi, Benjamin M. Gaub, Benjamin Sivyer, John G. Flannery, Ehud Y. Isacoff
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09124-x