Functional and Morphological Correlates in the Drosophila LRRK2 loss-of-function Model of Parkinson's Disease: Drug Effects of Withania somnifera (Dunal) Administration.

The common fruit fly Drosophila melanogaster (Dm) is a simple animal species that contributed significantly to the development of neurobiology whose leucine-rich repeat kinase 2 mutants (LRRK2) loss-of-function in the WD40 domain represent a very interesting tool to look into physiopathology of Park...

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Main Authors: Francescaelena De Rose, Roberto Marotta, Simone Poddighe, Giuseppe Talani, Tiziano Catelani, Maria Dolores Setzu, Paolo Solla, Francesco Marrosu, Enrico Sanna, Sanjay Kasture, Elio Acquas, Anna Liscia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4699764?pdf=render