Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions

Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions

Human pregnancy-specific glycoproteins (PSGs) serve immunomodulatory and pro-angiogenic functions during pregnancy and are mainly expressed by syncytiotrophoblast cells. While PSG mRNA expression in extravillous trophoblasts (EVTs) was reported, the proteins were not previously detected. By immunohi...

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Bibliographic Details
Main Authors: Shemona Rattila, Caroline E. E. Dunk, Michelle Im, Olga Grichenko, Yan Zhou, Maria Yanez-Mo, Sandra M. Blois, Kenneth M. Yamada, Offer Erez, Nardhy Gomez-Lopez, Stephen J. Lye, Boris Hinz, Roberto Romero, Marie Cohen, Gabriela Dveksler
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
pregnancy-specific glycoproteins
extravillous trophoblasts
integrin α5β1
adhesion
migration
preeclampsia
Online Access:https://www.mdpi.com/2073-4409/8/11/1369

Internet

https://www.mdpi.com/2073-4409/8/11/1369

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