α-Conotoxin TxIB: A Uniquely Selective Ligand for α6/α3β2β3 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Conditioned Place Preference in Mice

α-Conotoxin TxIB: A Uniquely Selective Ligand for α6/α3β2β3 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Conditioned Place Preference in Mice

&#945;-Conotoxin TxIB is a specific antagonist of &#945;6/&#945;3&#946;2&#946;3(&#945;6&#946;2*) nicotinic acetylcholine receptor (nAChR) with an IC<sub>50</sub> of 28 nM. Previous studies have shown that &#945;6&#946;2* nAChRs are abundantly expressed...

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Bibliographic Details
Main Authors: Shen You, Xiaodan Li, Jian Xiong, Xiaoyu Zhu, Dongting Zhangsun, Xiaopeng Zhu, Sulan Luo
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Marine Drugs
Subjects:
nicotine addiction
nAChRs
conditioned place preference (CPP)
neurotransmitters
Online Access:https://www.mdpi.com/1660-3397/17/9/490

Internet

https://www.mdpi.com/1660-3397/17/9/490

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