Persistence of pro-arrhythmic spatio-temporal calcium patterns in atrial myocytes: a computational study of ping waves

Clusters of ryanodine receptors within atrial myocytes are confined to spatially separated layers. In many species, these layers are not juxtaposed by invaginations of the plasma membrane, so that calcium-induced-calcium signals rely on centripetal propagation rather than voltage-synchronised chann...

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Bibliographic Details
Main Authors: Rüdiger eThul, Stephen eCoombes, Martin D Bootman
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00279/full