Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs) (hiPSC-CMs) are a promising cell source for disease modeling, myocardial regeneration, and drug assessment. However, hiPSC-CMs have certain immature fetal CM-like properties that are different from the characteristics of adult C...

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Bibliographic Details
Main Authors: Liang Ye, Xinyuan Zhang, Qin Zhou, Bin Tan, Hao Xu, Qin Yi, Liang Yan, Min Xie, Yin Zhang, Jie Tian, Jing Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hiPSCs
hiPSC-CMs
AMPK
mitochondrial
cardiomyocyte maturation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.644667/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.644667/full

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