Increased EGFR Phosphorylation Correlates with Higher Programmed Death Ligand-1 Expression: Analysis of TKI-Resistant Lung Cancer Cell Lines

Despite the recent development of immunotherapies that target programmed death-1 (PD-1) or programmed death ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) treatment, these therapies are less effective in NSCLC patients with epidermal growth factor receptor (EGFR) mutations. However, the mole...

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Bibliographic Details
Main Authors: Kenichi Suda, Leslie Rozeboom, Koh Furugaki, Hui Yu, Mary Ann C. Melnick, Kim Ellison, Christopher J. Rivard, Katerina Politi, Tetsuya Mitsudomi, Fred R. Hirsch
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/7694202