Differential Regulation of the Three Eukaryotic mRNA Translation Initiation Factor (eIF) 4Gs by the Proteasome

Differential Regulation of the Three Eukaryotic mRNA Translation Initiation Factor (eIF) 4Gs by the Proteasome

The 4G family of eukaryotic mRNA translation initiation factors is composed of three members (eIF4GI, eIF4GII, and DAP5). Their specific roles in translation initiation are under intense investigations, but how their respective intracellular amounts are controlled remains poorly understood. Here we...

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Bibliographic Details
Main Authors: Amandine Alard, Catherine Marboeuf, Bertrand Fabre, Christine Jean, Yvan Martineau, Frédéric Lopez, Patrice Vende, Didier Poncet, Robert J. Schneider, Corinne Bousquet, Stéphane Pyronnet
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
mRNA translation
eIF4G
DAP5
PEST
NQO1
NRF2
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00254/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00254/full

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